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Proteins and Peptides

ARID1A blocking peptide

Product Sizes
50 ug
£196.00
GTX31619-PEP-50UG
About this Product
SKU:
GTX31619-PEP
Additional Names:
At-Rich Interaction Domain 1A , B120 , Baf250 , Baf250A , Bm029 , C1Orf4 , Css2 , Eld , Mrd14 , Osa1 , P270 , Smarcf1 , Held , Hosa1 , Arid1A
Application:
Block/Inhibit/Neutralise
Buffer:
PBS, 0.1% BSA, 0.02% Sodium azide.
Concentration:
200 ug/ml
Extra Details:
This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isof
Immunogen:
AT-rich interaction domain 1A
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
GeneTex
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides