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Antibodies
Product Sizes
100 ug
£509.00
GTX31469-100UG
About this Product
SKU:
GTX31469
Additional Names:
growth factor receptor bound protein 10 , GRB-IR , Grb-10 , IRBP , MEG1 , RSS
Application:
ELISA, IHC-Paraffin, Western Blot
Buffer:
PBS, 0.02% Sodium azide.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]
Host:
Rabbit
Immunogen:
GRB10 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human GRB10.The immunogen is located within amino acids 440 - 490 of GRB10.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Specificity:
At least three isoforms of GRB10 are known to exist; this antibody will detect all three isoforms.
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Polyclonal Antibody