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Product Sizes
50 ug
£196.00
GTX28430-50UG
About this Product
SKU:
GTX28430
Additional Names:
B Cell Cll/Lymphoma 10 , Carmen , Ciper , Clap , Imd37 , C-E10 , Me10 , Bcl10
Application:
Block/Inhibit/Neutralise
Buffer:
PBS, 0.1% BSA, 0.02% Sodium azide.
Concentration:
0.20 mg/ml
Extra Details:
Bcl10, also designated as CIPER, mE10, cE10, CARMEN, and CLAP, is an N-terminal CARD (Caspase Recruitment Domain) containing protein. It is a cellular homologue of the equine herpesvirus-2 protein E-10 (vCLAP). Bcl 10 was implicated in the regulation of apoptosis by interacting with caspase 9, enhancing procaspase 9 processing, and triggering its activation when overexpressed in the cell. Bcl10 cellular overexpression induces JNK, p38, and NF-kappaB activation. Deregulation of Bcl10 expression was also demonstrated to be involved in cellular oncogenesis.
Immunogen:
B-cell CLL/lymphoma 10
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
GeneTex
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides