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Antibodies

PAPP A antibody [10E2]

Product Sizes
100 ug
£372.00
GTX28347-100UG
About this Product
SKU:
GTX28347
Additional Names:
pappalysin 1 , ASBABP2 , DIPLA1 , IGFBP-4ase , PAPA , PAPP-A , PAPPA1
Application:
ELISA, Immunoassay, Western Blot
Buffer:
PBS, 0.09% Sodium azide.
translate.label.attr.clone:
10E2
Clonality:
Monoclonal
Extra Details:
This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). Following IGFBP cleavage, insulin growth factors dissociate from IGFBPs and bind to IGF receptors, resulting in activation of the IGF pathway. The encoded protein plays a role in bone formation, inflammation, wound healing and female fertility. Enhanced expression of this protein is associated with diabetic nephropathy in human patients and this protein may promote tumor invasion and growth in various human cancers. [provided by RefSeq, Aug 2017]
Host:
Mouse
Immunogen:
Purified human PAPP-A antigen
Isotype:
IgG2b
Physical State:
Liquid
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody