IL1 beta antibody [5C10]
Product Sizes
100 ug
£372.00
GTX28321-100UG
About this Product
- SKU:
- GTX28321
- Additional Names:
- interleukin 1 beta , IL-1 , IL1-BETA , IL1F2
- Application:
- ELISA, Immunocytochemistry, Immunofluorescence
- Buffer:
- PBS, 0.09% Sodium azide.
- translate.label.attr.clone:
- 5C10
- Clonality:
- Monoclonal
- Extra Details:
- The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
- Host:
- Mouse
- Immunogen:
- Recombinant beta human Interleukin-1
- Isotype:
- IgM
- Physical State:
- Liquid
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody does not inhibit the biological activity of IL-1.
- Storage Conditions:
- 2-8[o]C
- Supplier:
- GeneTex
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:Download
