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Antibodies

IL1 beta antibody [11E5]

Product Sizes
100 ug
£372.00
GTX28320-100UG
About this Product
SKU:
GTX28320
Additional Names:
interleukin 1 beta , IL-1 , IL1-BETA , IL1F2
Application:
ELISA, Immunohistochemistry
Buffer:
PBS, 0.09% Sodium azide.
translate.label.attr.clone:
11E5
Clonality:
Monoclonal
Extra Details:
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
Host:
Mouse
Immunogen:
Recombinant human IL-1, beta.
Isotype:
IgG1
Physical State:
Liquid
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
Does not inhibit the biological activity of IL-1.
Storage Conditions:
2-8[o]C
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody