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Antibodies

CD45 antibody [MEM-28] (PE-Cy7)

Product Sizes
100 tests
£370.00
GTX28216-10-100TESTS
About this Product
SKU:
GTX28216-10
Additional Names:
protein tyrosine phosphatase receptor type C , B220 , CD45 , CD45R , GP180 , L-CA , LCA , LY5 , T200
Application:
Flow Cytometry
Buffer:
PBS, 15mM Sodium azide.
translate.label.attr.clone:
MEM-28
Clonality:
Monoclonal
Conjugate:
R-PE-Cyanine 7
Extra Details:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
Host:
Mouse
Immunogen:
Human thymocytes and T lymphocytes.
Isotype:
IgG1
Physical State:
Liquid
Purification:
Size-exclusion Chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody reacts with all alternative forms of human CD45 antigen (Leukocyte Common Antigen).,We do not recommend use of this product for Horse.
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody