SIRP alpha antibody
Product Sizes
100 ug
£588.00
GTX28120-100UG
About this Product
- SKU:
- GTX28120
- Additional Names:
- BIT , CD172A , MFR , MYD1 , P84 , PTPNS1 , SHPS1 , SIRP , SIRPA , signal regulatory protein alpha , CD172a , SIRP alpha , CD172 alpha
- Application:
- ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
- Buffer:
- PBS, 0.02% Sodium azide.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. [provided by RefSeq, Jul 2008]
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to 17 amino acids within the last 50 amino acids at the C-terminus of human SIRPA Alpha. Accession no.: NP_542970 Gene ID: 140885
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody recognizes human SIRP alpha 1, 2, and 3.
- Storage Conditions:
- 2-8[o]C
- Supplier:
- GeneTex
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:Download
