IL1 Receptor 2 antibody
Product Sizes
500 ul
£486.00
GTX27748-500UL
About this Product
- SKU:
- GTX27748
- Application:
- Immunoassay
- Buffer:
- PBS, 0.02% Sodium azide.
- Clonality:
- Polyclonal
- Concentration:
- 0.1 mg/ml
- Extra Details:
- The IL-1 system includes two agonists (IL-1a and IL-1b), converting enzymes, antagonists, two receptors (IL-1 RI and IL-1 RII) and the IL-1 receptor accessory protein. The IL-1 RII is part of the antagonistic IL-1 mechanism. It is also known as decoy receptor and is a non signaling molecule which functions by capturing IL-1 and preventing it from interacting with the signaling IL-1 RI. The decoy IL-1 RII can after binding to IL-1 also recruit the IL-1 receptor accessory protein and thus inhibit by co-receptor competition. Further a soluble form of IL-1 RII exists which is shed, a process in which matrix metalloproteases have been found to play a role, by various cells including monocytes, polymorphonuclear cells, B cells and fibroblasts.
- Host:
- Rabbit
- Isotype:
- IgG
- Physical State:
- Liquid
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody reacts specificly with Human IL-1 RII.
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:Download
