ANP32A peptide
Product Sizes
50 ug
£196.00
GTX26240-50UG
About this Product
- SKU:
- GTX26240
- Additional Names:
- Acidic Nuclear Phosphoprotein 32 Family Member A , C15Orf1 , Hppcn , I1Pp2A , Lanp , Mapm , Phap1 , Phapi , Pp32 , Anp32A
- Application:
- Block/Inhibit/Neutralise
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Concentration:
- 0.20 mg/ml
- Extra Details:
- Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after release from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activates procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-mediated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-mediated cell transformation.
- Immunogen:
- acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- GeneTex
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Manufacturer's Data Sheet:Download
