APAF1 peptide
Product Sizes
500 ul
£184.00
GTX22446-500UL
About this Product
- SKU:
- GTX22446
- Additional Names:
- apoptotic peptidase activating factor 1 , APAF-1 , CED4
- Application:
- Immunoprecipitation
- Buffer:
- PBS, BSA, 0.1% Sodium azide.
- Concentration:
- 0.2 mg/ml
- Extra Details:
- This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Immunogen:
- apoptotic peptidase activating factor 1
- Physical State:
- Liquid
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- GeneTex
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Manufacturer's Data Sheet:Download
