IL1 beta antibody
Product Sizes
100 ug
£429.00
GTX22105-100UG
About this Product
- SKU:
- GTX22105
- Additional Names:
- interleukin 1 beta , IL-1 , IL1-BETA , IL1F2
- Application:
- Block/Inhibit/Neutralise, ELISA, Flow Cytometry, IHC-Frozen, IHC-Paraffin, Immunoprecipitation, Western Blot
- Buffer:
- 20mM Potassium Phosphate, 150mM NaCl, no preservatives.
- Clonality:
- Polyclonal
- Concentration:
- 2 mg/ml
- Extra Details:
- Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence.
- Host:
- Rabbit
- Immunogen:
- This antibody was prepared by repeated immunizations with recombinant human IL-1s produced in E.coli. The MW of the recombinant 153 aa IL-1s was 17 kDa with the N-terminal amino acid at position alanine 117. This cleavage site is generated by the IL-1s.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Ion Exchange
- Reactivities:
- Canine, Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- Primarily directed against mature 17kDa human IL-1beta. In ELISA formats and other immunoreactive assays, the antibody will recognize 10% of the non-denatured (native) 31kDa IL-1beta precursor containing samples, but will detect all of the 17kDa mature molecule. Also detects primate IL-1beta in the same formats using similar dilutions.The antiserum does not recognize human IL-1alpha.
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:Download
