CD68 antibody [KP1] (ready-to-use)
Product Sizes
6 ml
£458.00
GTX20845-6ML
About this Product
- SKU:
- GTX20845
- Additional Names:
- CD68 molecule , GP110 , LAMP4 , SCARD1
- Application:
- IHC-Paraffin
- Buffer:
- PBS, 0.09% Sodium azide.
- translate.label.attr.clone:
- KP1
- Clonality:
- Monoclonal
- Extra Details:
- This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
- Host:
- Mouse
- Immunogen:
- Subcellular fraction of human alveolar macrophages.
- Isotype:
- IgG1
- Physical State:
- Liquid
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is specific to macrophages in a wide variety of human tissues. It reacts with myeloid precursors and peripheral blood granulocytes. It also stains a cell population known as plasmacytoid T cells.
- Storage Conditions:
- 2-8[o]C
- Supplier:
- GeneTex
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:Download
