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Product Sizes
100 ug
£347.00
GTX20050-100UG
About this Product
SKU:
GTX20050
Additional Names:
Subunit P40 , Natural Killer Cell Stimulatory Factor2 , Natural Killer Cell Stimulatory Factor 2 , Interleukin 12B , 40 kD Subunit , Cytotoxic lymphocyte maturation factor 40 kDa subunit , T cell stimulating factor , Cytotoxic lymphocyte maturation factor40 kDa subunit , CLMF2 , Interleukin12B , TSF , Cytotoxic Lymphocyte Maturation Factor 2 , IL12 , Cytotoxic Lymphocyte Maturation Factor2 , HGNC:5970 , IL1 , NKSF2 , CLMF , IL-12B , NKSF , IL 12B , IL12B
Application:
ELISA, IHC-Frozen, Radioimmunoassay
Buffer:
PBS, no preservatives.
Clonality:
Monoclonal
Concentration:
0.7 mg/ml
Extra Details:
IL12 is a heterodimeric cytokine comprised of p35 and p40 subunits. IL12 plays a central role in mediating cell mediated immunity, promoting differentiation of CD4+ T cells to the Th1 subset and of CD8+ T cells into mature cytotoxic T lymphocytes (CTLs). IL12 is a potent stimulator of NK cells. IL12 therapy has been suggested as a method of enhancing cytocidal anti tumour immune responses.
Host:
Mouse
Immunogen:
Recombinant human interleukin-12 produced in Baculovirus.
Isotype:
IgG1
Physical State:
Liquid
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
Recognises p35/40 heterodimer and p40. Used against CCHO and Baculovirus derived recombinant IL-12. Reacts with stimulated and unstimulated monocytes.
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody