CD3 epsilon antibody
Product Sizes
100 ug
£347.00
GTX20022-100UG
About this Product
- SKU:
- GTX20022
- Additional Names:
- CD3e molecule , IMD18 , T3E , TCRE
- Application:
- Flow Cytometry, IHC-Frozen, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Radioimmunoassay, Western Blot
- Buffer:
- PBS, no preservatives.
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
- Host:
- Mouse
- Immunogen:
- Human infant thymocytes and Sezary cells
- Isotype:
- IgG1
- Physical State:
- Liquid
- Purification:
- Protein A Purified
- Reactivities:
- Human, Porcine
- Shipping Conditions:
- Blue Ice
- Specificity:
- Detects the non-glycosylated epsilon chain of CD3 (MW 20kD) which is closely associated on the lymphocyte cell surface with the T cell antigen receptor (TCR).The antibody reacts with T cells in the thymus, bone marrow, and peripheral blood and is able to induce proliferation of mature thymocytes and T cells with, and without the presence of IL-2.The majority of T cell neoplasms are positive with t
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:Download
