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Antibodies

IL2 Receptor alpha antibody [IL2RA/2395]

Product Sizes
100 ug
£578.00
GTX18115-100UG
About this Product
SKU:
GTX18115
Additional Names:
CD25 , IDDM10 , IL2R , IL2RA , IMD41 , TCGFR , interleukin 2 receptor subunit alpha , p55 , IL2-R alpha
Application:
Detection/Quantitation, IHC-Paraffin
Buffer:
PBS, 0.05% BSA, 0.05% Sodium azide.
translate.label.attr.clone:
IL2RA/2395
Clonality:
Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
Host:
Mouse
Immunogen:
Recombinant fragment of human IL2RA protein (around aa 42-183) (exact sequence is proprietary)
Isotype:
IgG2b
Physical State:
Liquid
Purification:
protein a/g purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25.
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody