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Proteins and Peptides

Cyclin T1 blocking peptide

Product Sizes
50 ug
£196.00
GTX17200-PEP-50UG
About this Product
SKU:
GTX17200-PEP
Additional Names:
Cyclin T1 , Ccnt , Cyct1 , Hive1 , Ccnt1
Application:
Block/Inhibit/Neutralise
Buffer:
PBS, 0.1% BSA, 0.02% Sodium azide.
Concentration:
200 ug/ml
Extra Details:
This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
Immunogen:
cyclin T1
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
GeneTex
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides