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Proteins and Peptides

BCAR3 blocking peptide

Product Sizes
50 ug
£196.00
GTX17178-PEP-50UG
About this Product
SKU:
GTX17178-PEP
Additional Names:
Bcar3, Nsp Family Adaptor Protein , And-34 , Nsp2 , Sh2D3B , Bcar3
Application:
Block/Inhibit/Neutralise
Buffer:
PBS, 0.1% BSA, 0.02% Sodium azide.
Concentration:
200 ug/ml
Extra Details:
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Immunogen:
breast cancer anti-estrogen resistance 3
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
GeneTex
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides