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Antibodies

CD3 antibody [F7.2.38]

Product Sizes
500 ul
£920.00
GTX17143-500UL
About this Product
SKU:
GTX17143
Additional Names:
CD3d molecule , CD3-DELTA , IMD19 , T3D
Application:
IHC-Paraffin, Immunocytochemistry, Immunofluorescence
Buffer:
Tissue culture supernatant, 0.09% Sodium azide.
translate.label.attr.clone:
F7.2.38
Clonality:
Monoclonal
Extra Details:
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]
Host:
Mouse
Immunogen:
Purified CD3E EpsilonG GammaD Delta/CD3W Omega
Isotype:
IgG1
Physical State:
Liquid
Purification:
Unpurified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody labels CD3ε and is a useful tool for the identification of T cells and related neoplasms.
Storage Conditions:
2-8[o]C
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody