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Proteins and Peptides

APC5 blocking peptide

Product Sizes
50 ug
£196.00
GTX17060-PEP-50UG
About this Product
SKU:
GTX17060-PEP
Additional Names:
Anaphase Promoting Complex Subunit 5 , Apc5 , Anapc5
Application:
Block/Inhibit/Neutralise
Buffer:
PBS, 0.1% BSA, 0.02% Sodium azide.
Concentration:
200 ug/ml
Extra Details:
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008]
Immunogen:
anaphase promoting complex subunit 5
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
GeneTex
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides