CD3 antibody [SP7]
Product Sizes
500 ul
£613.00
GTX16669-500UL
About this Product
- SKU:
- GTX16669
- Additional Names:
- CD3d molecule , CD3-DELTA , IMD19 , T3D
- Application:
- Flow Cytometry, IHC-Frozen, IHC-Paraffin, Immunocytochemistry, Immunofluorescence
- Buffer:
- Tissue culture supernatant, 0.09% Sodium azide.
- translate.label.attr.clone:
- SP7
- Clonality:
- Monoclonal
- Extra Details:
- The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]
- Host:
- Rabbit
- Immunogen:
- A synthetic 13-mer peptide corresponding to aa 156-168 of the E Epsilon chain of human CD3 protein.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Unpurified
- Reactivities:
- Human, Mouse, Porcine, Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody reacts with the intracytoplasmic portion of the CD3 antigen expressed by T cells. It stains human T cells in both the cortex and medulla of the thymus and in peripheral lymphoid tissues.
- Storage Conditions:
- 2-8[o]C
- Supplier:
- GeneTex
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:Download
