Apolipoprotein B antibody [F2C4]
Product Sizes
100 ug
£486.00
GTX15664-100UG
About this Product
- SKU:
- GTX15664
- Additional Names:
- apolipoprotein B , FLDB , LDLCQ4 , apoB-100 , apoB-48
- Application:
- ELISA, IHC-Paraffin, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Radioimmunoassay
- Buffer:
- 10mM Potassium Phosphate, 135mM NaCl, 2.5mM KCl, 0.1% BSA, 0.05% Sodium azide.
- translate.label.attr.clone:
- F2C4
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]
- Host:
- Mouse
- Immunogen:
- Purified human serum LDL
- Isotype:
- IgG2a
- Physical State:
- Liquid
- Purification:
- Ion Exchange
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:Download
