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Antibodies

C/EBP beta antibody [1H7]

Product Sizes
50 ug
£429.00
GTX15050-50UG
About this Product
SKU:
GTX15050
Additional Names:
CCAAT/enhancer binding protein (C/EBP), beta , C/EBPbeta , CRP2 , IL-6DBP , LAP , LIP , NF-IL6 , NF-M , Nfil6
Application:
ChIP, Gel Shift/EMSA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Buffer:
PBS, 0.1% BSA, 0.05% Sodium azide.
translate.label.attr.clone:
1H7
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
The C/EBP (CCAAT/enhancer binding protein) family of transcription factors--alpha, beta, delta, and epsilon)--are widely expressed proteins found in a variety of tissues.? These domains contain an evolutionarily conserved five-amino acid motif (the regulatory domain motif RDM) that conforms to the consensus sequence (I/V/L) KXEP.? One of the major roles of these transcription factors is that of metabolic regulation in liver and fat cells.? Studies suggest that these transcription factors act in a cascade aiding in the development of the adipose cell. Three C/EBP beta isoforms (LAP*, LAP, and LIP) arise from different translation initiation and display different function in gene regulation.? From a neurological standpoint, C/EBPs have been implicated in the mediation of nerve growth factor, altering synaptic plasticity, and mediation of inflammatory response in AD patients.
Host:
Mouse
Immunogen:
Recombinant mouse LIP.
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Mouse, Rat
Shipping Conditions:
Blue Ice
Specificity:
This antibody detects the LAP*, LAP and LIP isoforms of C/EBP beta.
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody