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Antibodies

CD11a antibody [R7-1]

Product Sizes
500 ug
£400.00
GTX14215-500UG
About this Product
SKU:
GTX14215
Additional Names:
CD11A,ITGAL,LFA1,LFA1A,integrin subunit alpha L,CD11a,LFA-1
Application:
Cell-based/Functional Assay, Flow Cytometry
Buffer:
Filter-sterilized PBS, no preservatives.
translate.label.attr.clone:
R7-1
Clonality:
Monoclonal
Extra Details:
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Host:
Mouse
Immunogen:
integrin subunit alpha L
Isotype:
IgG1
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody recognizes an epitope within the I-domain of LFA-1α.
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody