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Antibodies

CHRFAM7A antibody [N1N3]

Product Sizes
25 ul
£139.00
GTX121209-25UL
100 ul
£354.00
GTX121209-100UL
About this Product
SKU:
GTX121209
Additional Names:
CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion , CHRNA7 , CHRNA7-DR1 , D-10 , NACHRA7
Application:
Western Blot
Buffer:
0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
translate.label.attr.clone:
N1N3
Clonality:
Polyclonal
Concentration:
0.56 mg/ml
Extra Details:
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq]
Host:
Rabbit
Immunogen:
Recombinant protein encompassing a sequence within the center region of human CHRFAM7A. The exact sequence is proprietary.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Polyclonal Antibody