4-1BBL / CD137L antibody [N2C3]
Product Sizes
25 ul
£139.00
GTX117355-25UL
100 ul
£354.00
GTX117355-100UL
About this Product
- SKU:
- GTX117355
- Additional Names:
- TNF superfamily member 9 , 4-1BB-L , CD137L , TNLG5A
- Application:
- Immunoprecipitation, Western Blot
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- translate.label.attr.clone:
- N2C3
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the Extracellular domain of human TNFSF9. The exact sequence is proprietary.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:Download
