GADD153 antibody [9C8]
Product Sizes
50 ug
£429.00
GTX11419-50UG
About this Product
- SKU:
- GTX11419
- Additional Names:
- DNA damage inducible transcript 3 , AltDDIT3 , C/EBPzeta , CEBPZ , CHOP , CHOP-10 , CHOP10 , GADD153
- Application:
- IHC-Frozen, IHC-Paraffin, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
- Buffer:
- PBS, 0.1% BSA, 0.05% Sodium azide.
- translate.label.attr.clone:
- 9C8
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]
- Host:
- Mouse
- Immunogen:
- A bacterially expressed, mouse CHOP fusion protein.
- Isotype:
- IgG2b
- Physical State:
- Liquid
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rabbit, Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- Clone 9C8 has been shown to recognize an epitope in the N-terminal region of CHOP
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:Download
