CD22 antibody [C2C3], C-term
Product Sizes
25 ul
£139.00
GTX114015-25UL
100 ul
£354.00
GTX114015-100UL
About this Product
- SKU:
- GTX114015
- Additional Names:
- CD22 molecule , SIGLEC-2 , SIGLEC2
- Application:
- Western Blot
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- translate.label.attr.clone:
- C2C3
- Clonality:
- Polyclonal
- Concentration:
- 0.79 mg/ml
- Extra Details:
- Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the Extracellular domain of human CD22. The exact sequence is proprietary.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:Download
