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Antibodies

GADD153 antibody [N1C3]

Product Sizes
25 ul
£139.00
GTX112827-25UL
100 ul
£354.00
GTX112827-100UL
About this Product
SKU:
GTX112827
Additional Names:
DNA damage inducible transcript 3 , AltDDIT3 , C/EBPzeta , CEBPZ , CHOP , CHOP-10 , CHOP10 , GADD153
Application:
IHC-Paraffin, Immunohistochemistry, Western Blot
Buffer:
PBS, 20% Glycerol, 0.025% ProClin 300.
translate.label.attr.clone:
N1C3
Clonality:
Polyclonal
Concentration:
0.95 mg/ml
Extra Details:
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq]
Host:
Rabbit
Immunogen:
Full length human GADD153 Recombinant protein.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Specificity:
KO/KD validation is based on customer review data.
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Polyclonal Antibody