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Antibodies

TLR4 antibody [HTA125] (PE)

Product Sizes
50 tests
£429.00
GTX11227-50TESTS
About this Product
SKU:
GTX11227
Additional Names:
toll like receptor 4 , ARMD10 , CD284 , TLR-4 , TOLL
Application:
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Buffer:
PBS, 1% BSA, 5% Sucrose, 0.09% Sodium azide.
translate.label.attr.clone:
HTA125
Clonality:
Monoclonal
Conjugate:
R-PE
Extra Details:
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Host:
Mouse
Immunogen:
Ba/F3 cell line expressing TLR4 (CD284).
Isotype:
IgG2a
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Canine, Guinea Pig, Human, Non-human Primate, Porcine
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody