CD3 epsilon antibody [CD3-12]
Product Sizes
100 ug
£403.00
GTX11089-100UG
About this Product
- SKU:
- GTX11089
- Additional Names:
- CD3e molecule , IMD18 , T3E , TCRE
- Application:
- Flow Cytometry, IHC-Frozen, IHC-Paraffin, Immunocytochemistry, Immunofluorescence, Western Blot
- Buffer:
- PBS, 0.09% Sodium azide.
- translate.label.attr.clone:
- CD3-12
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
- Host:
- Rat
- Immunogen:
- Synthetic peptide sequence derived from cytoplasmic epitope of CD3 (Glu-Arg-Pro-Pro-Pro-Val-Pro-Asn-Pro-Asp-Tyr-Glu-Pro-Cys) (ERPPPVPNPDYEPC)
- Isotype:
- IgG1
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Amphibian, Avian, Bovine, Canine, Feline, Horse, Human, Mouse, Non-human Primate, Other Mammal, Porcine, Rabbit
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody may not be suitable for human IHC-P assay, as its human reactivity is based on WB testing.This antibody has been specifically raised against an epitope within the epsilon peptide chain, highly conserved among species clone CD3-12 has a very broad species crossreactivity for the CD3 marker.
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:Download
