GSTA1 antibody
Product Sizes
25 ul
£139.00
GTX108012-25UL
100 ul
£354.00
GTX108012-100UL
About this Product
- SKU:
- GTX108012
- Additional Names:
- glutathione S-transferase alpha 1 , GST-epsilon , GST2 , GSTA1-1 , GTH1
- Application:
- IHC-Paraffin, Immunocytochemistry, Immunofluorescence, Western Blot
- Buffer:
- 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
- Clonality:
- Polyclonal
- Concentration:
- 6 mg/ml
- Extra Details:
- Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq]
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to human GSTA1
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- Based on sequence homology, this antibody may cross react with other GSTA family members.
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:Download
