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Antibodies

ATXN10 antibody

Product Sizes
25 ul
£139.00
GTX105440-25UL
100 ul
£354.00
GTX105440-100UL
About this Product
SKU:
GTX105440
Additional Names:
ataxin 10 , E46L , HUMEEP , SCA10
Application:
IHC-Paraffin, Western Blot
Buffer:
PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
Clonality:
Polyclonal
Concentration:
0.78 mg/ml
Extra Details:
The autosomal dominant cerebellar ataxias (ADCAs) are a clinically and genetically heterogeneous group of disorders characterized by ataxia, dysarthria, dysmetria, and intention tremor. All ADCAs involve some degree of cerebellar dysfunction and a varying degree of signs from other components of the nervous system. A commonly accepted clinical classification (Harding, 1993) divides ADCAs into 3 different groups based on the presence or absence of associated symptoms such as brainstem signs or retinopathy. The presence of pyramidal and extrapyramidal symptoms and ophthalmoplegia makes the diagnosis of ADCA I, the presence of retinopathy points to ADCA II, and the absence of associated signs to ADCA III. Genetic linkage and molecular analyses revealed that ADCAs are genetically heterogeneous even within the various subtypes.[supplied by OMIM]
Host:
Rabbit
Immunogen:
Recombinant protein encompassing a sequence within the center region of human ATXN10. The exact sequence is proprietary.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Polyclonal Antibody