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Antibodies

IL10 Receptor alpha antibody

Product Sizes
25 ul
£139.00
GTX102731-25UL
100 ul
£354.00
GTX102731-100UL
About this Product
SKU:
GTX102731
Additional Names:
interleukin 10 receptor subunit alpha , CD210 , CD210a , CDW210A , HIL-10R , IL-10R1 , IL10R
Application:
IHC-Paraffin, Western Blot
Buffer:
PBS, 20% Glycerol, 0.025% ProClin 300.
Clonality:
Polyclonal
Concentration:
1.68 mg/ml
Extra Details:
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq]
Host:
Rabbit
Immunogen:
Recombinant protein encompassing a sequence within the Intracellular domain of human IL10 Receptor alpha. The exact sequence is proprietary.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Polyclonal Antibody