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Antibodies
Product Sizes
25 ul
£139.00
GTX100513-25UL
100 ul
£354.00
GTX100513-100UL
About this Product
SKU:
GTX100513
Additional Names:
histone deacetylase 1 , GON-10 , HD1 , KDAC1 , RPD3 , RPD3L1
Application:
ChIP, IHC-Frozen, IHC-Paraffin, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
PBS, 20% Glycerol, 0.01% Thimerosal.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq]
Host:
Rabbit
Immunogen:
Recombinant protein encompassing a sequence within the center region of human HDAC1. The exact sequence is proprietary.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Fish, Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Specificity:
KO/KD validation is based on published data (PMID: 27065869 and 30242288).
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Polyclonal Antibody