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Antibodies

CD16 antibody [KD1] (PE)

Product Sizes
100 tests
£602.00
GTX04886-08-100TESTS
About this Product
SKU:
GTX04886-08
Additional Names:
Fc fragment of IgG receptor IIIa , Fc fragment of IgG receptor IIIb , CD16 , CD16A , FCG3 , FCGR3 , FCGRIII , FCR-10 , FCRIII , FCRIIIA , IGFR3 , IMD20 , CD16 , CD16A , CD16b , FCG3 , FCGR3 , FCGR3A , FCR-10 , FCRIII , FCRIIIb
Application:
Flow Cytometry
Buffer:
PBS, 1% BSA, 5% Sucrose, 0.09% Sodium Azide.
translate.label.attr.clone:
KD1
Clonality:
Monoclonal
Conjugate:
R-PE
Extra Details:
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Host:
Mouse
Immunogen:
A polyclonal population of NK cells.
Isotype:
IgG2a
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Bovine, Human, Other Mammal, Sheep
Shipping Conditions:
Blue Ice
Specificity:
Clone KD1 recognizes both forms of CD16 and will therefore recognize all cell types expressing CD16.,We do not recommend use of this product for Dog,Rat.
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody