Human H-Ras (G12V mutant) protein, His tag
Product Sizes
50 ug
GTX04505-PRO-50UG
About this Product
- SKU:
- GTX04505-PRO
- Additional Names:
- HRas proto-oncogene, GTPase , C-BAS/HAS , C-H-RAS , C-HA-RAS1 , CTLO , H-RASIDX , HAMSV , HRAS1 , KRAS , KRAS2 , Ki-Ras , RASH1 , RASK2 , c-K-ras , c-Ki-ras , p21ras
- Buffer:
- Reconstitute with ddH₂O to 0.2 mg/mL. Do not vortex. Lyophilized from 10 mM Hepes (pH7.4), 500 mM NaCl, 5% trehalose, no preservatives.
- Extra Details:
- This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, cognitive disability, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
- Immunogen:
- HRas proto-oncogene, GTPase
- Physical State:
- Lyophilized
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C concentrated solution. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- GeneTex
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:Download
