Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies
Product Sizes
100 ug
£533.00
GTX03379-100UG
About this Product
SKU:
GTX03379
Additional Names:
Fc fragment of IgG receptor IIIa , CD16 , CD16A , FCG3 , FCGR3 , FCGRIII , FCR-10 , FCRIII , FCRIIIA , IGFR3 , IMD20
Application:
ELISA, Flow Cytometry, IHC-Paraffin, Immunocytochemistry, Immunofluorescence
Buffer:
4mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, 0.05mg Sodium azide.
Clonality:
Polyclonal
Concentration:
5 mg/ml
Extra Details:
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Host:
Rabbit
Immunogen:
E. coli-derived human CD16 recombinant protein (Position: Q101-D166).
Isotype:
IgG
Physical State:
Liquid
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Polyclonal Antibody