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Antibodies

IL1 beta antibody [MT175]

Product Sizes
250 ug
£458.00
GTX02972-250UG
About this Product
SKU:
GTX02972
Additional Names:
IL1,IL1B,IL1BETA,IL1F2,interleukin 1 beta,IL1 beta,IL-1B
Application:
ELISA
Buffer:
PBS, 0.02% Sodium azide.
translate.label.attr.clone:
MT175
Clonality:
Monoclonal
Concentration:
0.5 mg/ml
Extra Details:
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
Host:
Mouse
Immunogen:
Recombinant human IL-1B Beta
Isotype:
IgG1
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody is able to detect native and recombinant human IL-1, binds to the pro-form and active form of IL-1, and has no cross-reactivity with IL-1.
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody