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Antibodies

IL10 antibody [9D7]

Product Sizes
250 ug
£486.00
GTX02950-250UG
About this Product
SKU:
GTX02950
Additional Names:
CSIF,GVHDS,IL10,IL10A,TGIF,interleukin 10
Application:
ELISA
Buffer:
PBS, 0.02% Sodium azide.
translate.label.attr.clone:
9D7
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
Host:
Rat
Immunogen:
Recombinant human IL-10
Isotype:
IgG1
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody is able to detect native and recombinant human IL-10.
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody