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Proteins and Peptides

Human MMP7 protein (Active)

Product Sizes
20 ug
£306.00
GTX02553-PRO-20UG
About this Product
SKU:
GTX02553-PRO
Additional Names:
matrix metallopeptidase 7 , MMP-7 , MPSL1 , PUMP-1
Application:
Cell-based/Functional Assay
Buffer:
10mM HEPES, 5mM CaCl₂, 150mM NaCl, no preservatives.
Extra Details:
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers. [provided by RefSeq, Jan 2016]
Immunogen:
matrix metallopeptidase 7
Physical State:
Liquid
Purification:
Proprietary Chromatographic Technique
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
GeneTex
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes