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Proteins and Peptides

Mouse HEXA protein, His tag

Product Sizes
10 ug
£370.00
GTX00306-PRO-10UG
About this Product
SKU:
GTX00306-PRO
Additional Names:
hexosaminidase A , Hex-1
Application:
Cell-based/Functional Assay
Buffer:
Reconstitute with 20mM Tris and 150mM NaCl to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris, 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
Extra Details:
This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mice lacking the encoded protein exhibit accumulation of gangliosides in the brain and membranous cytoplasmic bodies in neurons. Certain mutations in the human ortholog of this gene cause Tay-Sachs disease. [provided by RefSeq, Aug 2016]
Immunogen:
hexosaminidase A
Physical State:
Lyophilized
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes