Anti-Hu CD42a PerCP-Cy[TM]5.5
Product Sizes
100 tests
£410.00
T9-732-100TESTS
About this Product
- SKU:
- T9-732
- Application:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- GR-P
- Conjugate:
- PerCP-Cyanine 5.5
- Extra Details:
- CD42a, also known as glycoprotein 9 (GPIX), composes together with GPIb alpha, GPIb beta and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular wight kininogen, TSP-1, integrin Mac-1 and P-selectin. Defects in the gene encoding CD42a are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.
- Immunogen:
- Human acute lymphoblastic leukemia cells
- Isotype:
- IgG1
- Reactivities:
- Canine, Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody GR-P (also known as GRP-P) recognizes an extracellular epitope of CD42a (glycoprotein 9), a 22 kDa transmembrane protein constitutively expressed on megakaryocytes and platelets.
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Exbio
- Type:
- Antibody
- FluoroFinder:
