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Antibodies

Anti-Hu CD209 PerCP-Cy[TM]5.5

Product Sizes
100 tests
£410.00
T9-640-100TESTS
About this Product
SKU:
T9-640
Application:
Flow Cytometry
CE/IVD:
RUO
translate.label.attr.clone:
UW60.1
Conjugate:
PerCP-Cyanine 5.5
Extra Details:
CD209, also known as DC-SIGN (dendritic cell-specific ICAM-3-grabbing nonintegrin) is a transmembrane receptor expressed on the surface of dendritic cells and macrophages, which recognizes numerous pathogens ranging from parasites to viruses. Its N-terminal domain is transmembrane, whereas a tandem-repeat neck domain and the C terminal C-type lectin carbohydrate recognition domain have dual function as a pathogen recognition receptor and a cell adhesion receptor. The neck region is responsible for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. A ligand of CD209 is also CD50 (ICAM-3).
Immunogen:
CD209-His-tagged fusion protein
Isotype:
IgG2a
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
The mouse monoclonal antibody UW60.1 recognizes an extracellular epitope of human CD209 (DC-SIGN), a 44 kDa transmembrane receptor, expressed on the surface of dendritic cells and macrophages.
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Exbio
Type:
Antibody
FluoroFinder: