Anti-Hu CD144 PE-Cy[TM]5
Product Sizes
100 tests
£278.00
T8-770-100TESTS
About this Product
- SKU:
- T8-770
- Application:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 55-7H1
- Conjugate:
- Cyanine 5
- Extra Details:
- CD144 / VE-cadherin (cadherin 5) is the major cadherin that is present at endothelial junctions. It is also strictly endothelial specific. Under vascular permeability increasing conditions (and also in capillaries and veins) CD144 is being phosphorylated, which promotes its rapid and reversible internalization. On the contrary, binding of p120 catenin (delta1 catenin) maintains CD144 localization at the plasma membrane, which stabilizes the junction and reduces vascular permeability.
- Immunogen:
- Human endothelial cells
- Isotype:
- IgG1, kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody 55-7H1 recognizes a calcium-independent extracellular epitope on CD144 (VE-cadherin, cadherin 5), an adhesion molecule expressed on endothelial cells.
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Exbio
- Type:
- Antibody
- FluoroFinder:
