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Antibodies

Anti-Hu CD34 PE-Cy[TM]5

Product Sizes
25 tests
£195.00
T8-664-25TESTS
100 tests
£349.00
T8-664-100TESTS
About this Product
SKU:
T8-664
Application:
Flow Cytometry
CE/IVD:
RUO
translate.label.attr.clone:
581
Conjugate:
Cyanine 5
Extra Details:
CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.
Isotype:
IgG1, kappa
Reactivities:
Human, Non-human Primate
Shipping Conditions:
Blue Ice
Specificity:
The mouse monoclonal antibody 581 reacts with an extracellular epitope of CD34, a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells; it is gradually lost on progenitor cells. The antibody recognizes the class III CD34 epitope resistant to neuraminidase, chymopapain and glycoprotease.
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Exbio
Type:
Antibody
FluoroFinder: