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Antibodies

Anti-Hu CD193 PE-Cy[TM]5

Product Sizes
100 tests
£278.00
T8-161-100TESTS
About this Product
SKU:
T8-161
Application:
Flow Cytometry
CE/IVD:
RUO
translate.label.attr.clone:
5E8
Conjugate:
Cyanine 5
Extra Details:
CD193 / CCR3 is a G-protein coupled receptor for several chemokines, namely CCL11 (eotaxin), CCL26 (eotaxin-3), CCL7 (MCP-4), or CCL5 (RANTES). It is highly expressed on eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. CD193 is the key eosinophil chemokine receptor responsible for regulation of eosinophil migration and function. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.
Immunogen:
human CD193 transfectants
Isotype:
IgG2b, kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
The mouse monoclonal antibody 5E8 recognizes an extracellular epitope of CD193 (chemokine receptor 3), an approximately 41 kDa protein expressed above all in eosinophils and basophils.
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Exbio
Type:
Antibody
FluoroFinder: