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Antibodies

Anti-Hu CD49b PE-DyLight[TM] 594

Product Sizes
100 tests
£310.00
T5-151-100TESTS
About this Product
SKU:
T5-151
Application:
Flow Cytometry
CE/IVD:
RUO
translate.label.attr.clone:
AK7
Conjugate:
R-PE-DyLight™ 594
Extra Details:
CD49b the integrin alpha 2 chain, associates with CD29 (integrin beta 1 chain) to form VLA-2 integrin complex, which plays a critical role in the processes of lymphocyte adhesion and activation. VLA-2 serves as a receptor for collagen, laminin, and fibronectin and also regulates the extracellular matrix synthesis and organization. CD49b has been used to identify NK cells, and coexpressed with CD223 (LAG-3) it identifies CD4+ T regulatory type 1 cells (Tr1).
Immunogen:
Human platelets
Isotype:
IgG1
Reactivities:
Human, Non-human Primate
Shipping Conditions:
Blue Ice
Specificity:
The mouse monoclonal antibody AK7 recognizes an extracellular epitope of CD49b, a 160-165 kDa alpha subunit of VLA-2 integrin complex expressed on platelets, megakaryocytes, activated T and B cells, monocytes, epithelial cells, endothelial cells and fibroblasts.
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Exbio
Type:
Antibody
FluoroFinder: