Anti-Hu CD11c APC-Cy[TM]7
Product Sizes
100 tests
£310.00
T4-529-100TESTS
About this Product
- SKU:
- T4-529
- Application:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- BU15
- Conjugate:
- APC-Cyanine 7
- Extra Details:
- CD11c (p150, alphaX integrin subunit) forms complex with CD18 (beta2 integrin subunit) and is expressed mainly on tissue macrophages and dendritic cells. CD11c binds to complement fragment iC3b, fibrinogen, VCAM-1 and ICAM-2 or e.g. CD90. Like other beta2 integrins, CD11c/CD18 plays roles in cell migration and phagocytosis. Moreover, interaction of CD11c/CD18 with plasminogen regulates plasmin activities, and interaction with heparin counteracts binding of iC3b.
- Immunogen:
- Dendritic cells of synovial fluid
- Isotype:
- IgG1, kappa
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody BU15 reacts with an extracellular epitope of CD11c (alphaX, p150), a 150 kDa integrin expressed mainly on dendritic cells and tissue macrophages.
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Exbio
- Type:
- Antibody
- FluoroFinder:
