Anti-Hu CD19 APC-Cy[TM]7
Product Sizes
25 tests
£175.00
T4-305-25TESTS
100 tests
£310.00
T4-305-100TESTS
About this Product
- SKU:
- T4-305
- Application:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- LT19
- Conjugate:
- APC-Cyanine 7
- Extra Details:
- CD19 is a transmembrane glycoprotein of Ig superfamily expressed by B cells from the time of heavy chain rearrangement until plasma cell differentiation. It forms a tetrameric complex with CD21 (complement receptor type 2), CD81 (TAPA-1) and Leu13. Together with BCR (B cell antigen receptor), this complex signals to decrease B cell treshold for activation by the antigen. Besides being signal-amplifying coreceptor for BCR, CD19 can also signal independently of BCR coligation and it turns out to be a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.
- Immunogen:
- Daudi human Burkitt lymphoma cell line
- Isotype:
- IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody LT19 reacts with an extracellular epitope of CD19 (B4), a 95 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on B lymphocytes and follicular dendritic cells; it is lost on plasma cells.
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Exbio
- Type:
- Antibody
- FluoroFinder:
